Optimal Mutation Rates in Dynamic Environments

نویسندگان

چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Optimal mutation rates in dynamic environments.

In this paper, we study the evolution of the mutation rate for simple organisms in dynamic environments. A model based on explicit population dynamics at the gene sequence level, with multiple fitness coding loci tracking a moving fitness peak in a random fitness background, is developed and an analytical expression for the optimal mutation rate is derived. The optimal mutation rate per genome ...

متن کامل

Optimal Mutation Rates in Genetic Search

The optimization of a single bit string by means of iterated mutation and selection of the best a Genetic Algorithm is dis cussed with respect to three simple tness functions The counting ones problem a standard binary encoded integer and a Gray coded integer optimization problem A mu tation rate schedule that is optimal with re spect to the success probability of mutation is presented for each...

متن کامل

Optimal Mutation Rates on Static Fitness Landscpes

We study the evolution of mutation rates for an asexual population living on a static fitness landscape, consisting of multiple peaks forming an evolutionary staircase. The optimal mutation rate is found by maximizing the diffusion towards higher fitness. Surprisingly the optimal genomic copying fidelity is given by Qopt = e − 1 ln ν (where ν is the genome length), independent of all other para...

متن کامل

Optimal bacteriophage mutation rates for phage therapy.

The mutability of bacteriophages offers a particular advantage in the treatment of bacterial infections not afforded by other antimicrobial therapies. When phage-resistant bacteria emerge, mutation may generate phage capable of exploiting and thus limiting population expansion among these emergent types. However, while mutation potentially generates beneficial variants, it also contributes to a...

متن کامل

On Recombination and Optimal Mutation Rates

We present empirical evidence from a wide range of problem characteristics suggesting that the value of optimal mutation rates in GAs di ers according to whether recombi nation is used or not Without recombina tion a regime that starts with a high muta tion rate decreasing it towards the end of the run appears to be optimal With recombina tion however the optimal strategy proves to be a constan...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Bulletin of Mathematical Biology

سال: 2002

ISSN: 0092-8240

DOI: 10.1006/bulm.2002.0314